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Jemperli Plus Chemotherapy Now FDA Approved for Front-Line Treatment of dMMR or MSI-H Endometrial Cancer
FDA Approvals, News & Updates
,
Endometrial Cancer
,
Gynecologic Cancer
August 2023, Vol 14, No 4
On
July 31, 2023
, the FDA approved a new indication for dostarlimab-gxly (Jemperli; GlaxoSmithKline), a PD-1 inhibitor, in combination with carboplatin and paclitaxel, followed by single-agent dostarlimab, for primary advanced or recurrent endometrial cancer that is mismatch repair deficient (dMMR), as determined by an FDA-approved test, or microsatellite instability-high (MSI-H).
Read More
Vanflyta Now Approved for Newly Diagnosed FLT3-ITD–Positive AML
FDA Approvals, News & Updates
,
Leukemia
,
Hematologic Malignancies
August 2023, Vol 14, No 4
On
July 20, 2023
, the FDA approved quizartinib (Vanflyta; Daiichi Sankyo) with standard cytarabine and anthracycline induction and cytarabine consolidation, and as maintenance monotherapy after consolidation chemotherapy, for the treatment of adults with newly diagnosed acute myeloid leukemia (AML) that is
FLT3
-internal tandem duplication (
ITD
)–positive, as detected by an FDA-approved test.
Read More
Talzenna Receives New Indication, With Enzalutamide, for Metastatic Castration-Resistant Prostate Cancer With HRR Gene Mutation
FDA Approvals, News & Updates
,
Prostate Cancer
August 2023, Vol 14, No 4
On
June 20, 2023
, the FDA approved a new indication for talazoparib (Talzenna; Pfizer), a poly (ADP-ribose) polymerase inhibitor, in combination with enzalutamide (Xtandi; Astellas) for homologous recombination repair (
HRR
) gene mutation–positive, metastatic castration-resistant prostate cancer. The FDA granted this application priority review.
Read More
U.S. Patients Rely On Generic Medicines But Increases In Drug Shortages Reflect Challenges To Their Long-Term Sustainability
By
Monét Stanford
Patient Advocacy
August 2023, Vol 14, No 4
Generic medicines are the backbone of the US prescription drug market, supplying more than 9 out of every 10 prescriptions. And the production of generic medicines overall has been remarkably stable—even during challenges such as the COVID-19 pandemic.
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Physician Debate: Is Chemotherapy Still the Backbone for CCA Treatment?
Cholangiocarcinoma
August 2023, Vol 14, No 4
At the 10th Annual Cholangiocarcinoma Foundation Conference, Rachna Shroff, MD, MS, Chief, Gastrointestinal Medical Oncology, and Director, Clinical Trials Office, University of Arizona Cancer Center, Tucson, and Madhulika Eluri, MD, Hematology/Oncology Fellow, The University of Texas MD Anderson Cancer Center, Houston, debated whether chemotherapy remains the backbone for cholangiocarcinoma (CCA) treatment or if it is time to move away from this therapeutic strategy.
Read More
Tornado Sweeps Through Pfizer’s Storage and Manufacturing Facility
FDA Approvals, News & Updates
Web Exclusives
On July 19, 2023, an EF3 tornado touched down in Rocky Mount, NC, badly damaging a Pfizer drug manufacturing facility that is responsible for producing nearly 25% of Pfizer’s sterile injectable medicines used in US hospitals.
Read More
Research Indicates Fewer People Understand the Link Between HPV and Certain Cancers
By
Phoebe Starr
Cancer Prevention
,
AACR 2023 Annual Meeting
June 2023, Vol 14, No 3 - Online Only
Vaccination against human papillomavirus (HPV) can prevent several types of cancer, including cervical, oral/oropharyngeal, penile, and anal cancers. Unfortunately, vaccination rates, as well as public knowledge regarding the link between HPV and these cancers, are lagging, according to research presented during the 2023 American Association for Cancer Research Annual Meeting.
Read More
Physician Shortages Forcing Medical Group Leaders to Be More Flexible in Their Staffing Models
By
MGMA Staff Members
Healthcare Administration
June 2023, Vol 14, No 3 - Online Only
An April 4, 2023, Medical Group Management Association
Stat
poll found that almost one-half (47%) of medical group leaders have added or created part-time or flexible-schedule physician roles in the past year, while 53% did not.
Read More
Long-Term Financial Toxicity Has Substantial Impact on HRQoL Among Partners of Colorectal Cancer Survivors
Survivorship
,
Financial Toxicity
June 2023, Vol 14, No 3 - Online Only
A new study has found that partners of colorectal cancer survivors experienced long-term financial toxicity that was associated with worse health-related quality of life due to systems- and individual-level behavioral factors.
Read More
National Black Family Cancer Awareness Week
Cancer Awareness
June 2023, Vol 14, No 3 - Online Only
National Black Family Cancer Awareness Week will be held June 15, 2023, through June 21, 2023.
Read More
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Home
Issues
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Personalized Medicine
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