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Articles
Articles
Anti-CD38 Antibodies in the Treatment of RRMM: Considerations for Pharmacists
Multiple Myeloma
2022 Year in Review - Multiple Myeloma
Implementation of a pharmacist on the healthcare team can have significant clinical and economic benefits.
Read More
Subcutaneous Isatuximab Administration by an On-Body Delivery System May Provide a More Convenient Option for Patients with RRMM
Multiple Myeloma
2022 Year in Review - Multiple Myeloma
Updated results from a phase 1 trial of subcutaneous isatuximab via OBDS continue to demonstrate an excellent local tolerability with comparable efficacy.
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First Results from a Phase 1 Study of BMS-986393, a GPRC5D-Targeted CAR T-Cell Therapy, in Patients with RRMM
Multiple Myeloma
2022 Year in Review - Multiple Myeloma
Preliminary data support the use of BMS-986393 in patients with RRMM despite prior BCMA-directed therapy.
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Subgroup Analysis of CANDOR-Evaluated Outcomes with Carfilzomib plus Dexamethasone and Daratumumab Based on Cytogenetic Risk
Multiple Myeloma
2022 Year in Review - Multiple Myeloma
Data from a subgroup analysis of CANDOR supported the efficacy of daratumumab plus carfilzomib and dexamethasone in RRMM, even in high-risk patients.
Read More
GC012F, an Autologous BCMA and CD19 Dual-Targeting CAR T-Cell Therapy, as First-Line Treatment for Transplant-Eligible Patients with Newly Diagnosed High-Risk Multiple Myeloma
Multiple Myeloma
2022 Year in Review - Multiple Myeloma
A phase 1 trial of GC012F demonstrated an overall response rate of 100% in high-risk, transplant-eligible patients with newly diagnosed multiple myeloma.
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Jaypirca Receives FDA Accelerated Approval for Relapsed or Refractory Mantle-Cell Lymphoma
FDA Approvals, News & Updates
,
Lymphoma
February 2023, Vol 14, No 1
On
January 27, 2023
, the FDA accelerated the approval of pirtobrutinib (Jaypirca; Eli Lilly) for the treatment of patients with relapsed or refractory mantle-cell lymphoma (MCL) after at least 2 lines of systemic therapy, including a Bruton tyrosine kinase (BTK) inhibitor.
Read More
FDA Grants Lunsumio Accelerated Approval for Relapsed or Refractory Follicular Lymphoma
FDA Approvals, News & Updates
,
Lymphoma
February 2023, Vol 14, No 1
On
December 22, 2022
, the FDA accelerated the approval of mosunetuzumab-axgb (Lunsumio; Genentech), a bispecific CD20-directed CD3 T-cell engager, for adults with relapsed or refractory follicular lymphoma after ≥2 lines of systemic therapy. The FDA granted this indication breakthrough therapy and orphan drug designations.
Read More
Results from Phase 3 Trial Show Similar Efficacy and Safety Outcomes with CT-P16 versus Bevacizumab in Patients with NSCLC
Biosimilars
Web Exclusives
One-year follow-up data from a phase 3 study found similar duration of response, time to progression (TTP), and survival rates with the biosimilar candidate CT-P16 compared with its reference drug, bevacizumab (Avastin), in the first-line treatment of patients with metastatic or recurrent nonsquamous non–small-cell lung cancer (NSCLC).
Read More
Biosimilar Substitution May Reduce Financial Risk to Providers in Value-Based Payment Models
By
Wayne Kuznar
Biosimilars
,
ASCO 2022 Highlights
February 2023, Vol 14, No 1
Providers participating in the Centers for Medicare & Medicaid Services’ (CMS’) value-based payment (VBP) models may realize a reduction in financial risk via biosimilar substitution.
Read More
Adding Radiation to Systemic Therapy Improves Survival in Patients with Advanced Hepatocellular Cancer
By
Phoebe Starr
ASTRO Meeting Highlights
,
Hepatocellular Carcinoma
February 2023, Vol 14, No 1
According to findings from a phase 3 trial presented at the American Society for Radiation Oncology Annual Meeting 2022, the addition of stereotactic body radiation therapy (SBRT) to sorafenib (Nexavar) can lengthen overall survival (OS) and delay tumor progression in patients with unresectable advanced hepatocellular cancer (HCC) without compromising quality of life.
Read More
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Home
Issues
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Personalized Medicine
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