November/December 2010, Vol 1, No 6

Bethesda, MD—Implementing and effectively using comparative effectiveness research (CER) and personalized medicine (PM) will require time and better communication among the research community conducting these types of studies and with the public that will be impacted by them, according to participants in a panel discussion on the societal implications of CER and PM held during the ECRI Institute’s Comparative Ef fectiveness and Personalized Medicine: An Essential Interface conference.

Bethesda, MD—Greater adoption of personalized medicine and comparative effectiveness research (CER) in healthcare will depend on coverage of these approaches by public and private payers. But payer evaluation of these approaches is hampered by legislative roadblocks and a lack of research in CER and slowness in adopting CER into clinical practice, according to speakers at a session of the ECRI Institute’s Comparative Effectiveness and Personalized Medicine: An Essential Interface conference.

Milan—Continuing first-line chemotherapy for metastatic breast cancer until disease progression significantly improves overall (OS) and progression free survival (PFS), according to a meta-analysis reported at the 35th ESMO Congress.

Milan—Because the toxicity profiles for the 3 monoclonal antibodies used in treating metastatic colorectal cancer (mCRC) differ, there are substantial differences in the cost of treating side effects, according to research presented at the 35th ESMO Congress.

Setting up a statewide cancer pathway program requires sophisticated data collection and analytic capability, as well as a collaborative mindset among participants, according to Kurt Neumann, MD, Medical Director of Managed Care and Quality Initiatives for the International Oncology Network, a division of Amerisource Bergen Specialty Group.

On November 2, 2010, the Centers for Medicare & Medicaid Services (CMS) issued its Physician Fee Schedule and Hospital Outpatient Prospective Payment System final rules for 2011.

Consolidation and cost pressures remain key concerns for community cancer centers, according to Christian Downs, MHA, JD, the executive director of the Association of Community Cancer Centers (ACCC).

National Harbor, MD—Multiple benefitswere observed for contralateral prophylactic mastectomy (CPM), including cost-effectiveness, in studies presented at the 2010 ASCO Breast Cancer Symposium by investigators from the Mayo Clinic, Rochester, MN.

Milan—Men with castration-resistant prostate cancer (CRPC) gained 4 months in overall survival (OS) when treated with the novel antiandrogen abiraterone acetate, data from a large randomized trial showed.