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Issues
2022
October 2022, Vol 13, No 5
October 2022, Vol 13, No 5
Researchers Discover How Air Pollution May Trigger Lung Cancer in Never-Smokers
By
Phoebe Starr
ESMO 2022 Highlights
October 2022, Vol 13, No 5
Although it is well established that air pollution is associated with lung cancer, how this occurs has not been well described. For the first time, researchers have identified the mechanism by which particulate matter in the air may lead to non–small-cell lung cancer (NSCLC) in people who have never smoked.
Read More
DETERMINATION Trial Confirms Importance of Individualizing Therapy for Newly Diagnosed Multiple Myeloma
By
Phoebe Starr
Hematologic Malignancies
October 2022, Vol 13, No 5
In the phase 3 DETERMINATION trial—in which patients with newly diagnosed multiple myeloma were randomly assigned to a standard triplet regimen with and without autologous stem-cell transplantation (ASCT), with all receiving lenalidomide (Revlimid) maintenance therapy until disease progression—patients with ASCT had significantly longer progression-free survival (PFS) versus those who did not, but no difference in overall survival (OS) was observed between the 2 treatment arms.
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A Path Toward Clinical Trial Diversity
By
Liz Beatty, Chief Strategy Officer, Inato
Disparities in Cancer Care
October 2022, Vol 13, No 5
Minority and marginalized communities have historically been underrepresented in local and federal governments and in dozens of private sectors globally. Pharma is no different; there exists a steep chasm that drugmakers have yet to bridge concerning research and trials.
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Increased Biosimilar Use Translates to Substantial Savings for Oncology Practices
By
Wayne Kuznar
Biosimilars
October 2022, Vol 13, No 5
The increased use of biosimilars within the US Oncology Network generated more than $6 million of savings in the Centers for Medicare & Medicaid Services’ Oncology Care Model (OCM) during the first half of 2020.
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Integrating Digital Health Technology into Cancer Care
By
Phoebe Starr
ESMO 2022 Highlights
October 2022, Vol 13, No 5
Digital health technologies have the potential to help transform patient care, but there are barriers that need to be overcome, said Deb Schrag, MD, MPH, George J.
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Novel Approach to the Treatment of Desmoid Tumors Shows Great Promise
By
Phoebe Starr
ESMO 2022 Highlights
October 2022, Vol 13, No 5
For the first time, a novel gamma secretase inhibitor has shown extremely promising results in desmoid tumors—a rare, benign, but potentially aggressive tumor type
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Adding Pembrolizumab to Chemotherapy Extends Survival in Women with Cervical Cancer Across Several Key Subgroups
By
Wayne Kuznar
Cervical Cancer
October 2022, Vol 13, No 5
The addition of pembrolizumab (Keytruda) to chemotherapy with or without bevacizumab (Avastin) resulted in significantly and clinically meaningful improvements in overall survival (OS) and progression-free survival (PFS) in women with cervical cancer.
Read More
CAR T-Cell Effective as Second-Line Treatment in Transplant-Ineligible Large B-Cell Lymphoma
By
Wayne Kuznar
Hematologic Malignancies
October 2022, Vol 13, No 5
More than 50% of adults with refractory or relapsed large B-cell lymphoma (LBCL) who were not deemed candidates for high-dose chemotherapy and hematopoietic stem-cell transplantation (HSCT) had complete responses (CRs) following treatment with the chimeric antigen receptor (CAR) T-cell therapy lisocabtagene maraleucel (Breyanzi).
Read More
GemCis with or without CPI-613 as First-Line Therapy for Patients with Advanced BTCs: The BilT-04 Study
Cholangiocarcinoma
October 2022, Vol 13, No 5
Patients with advanced biliary tract cancers (BTCs) have a poor prognosis despite systemic chemotherapy.
Read More
COVID-19’s Impact on Radiation Oncology and Healthcare
By
Ben Adams
;
Ron DiGiaimo, MBA, FACHE
;
Bri Driggers
COVID-19 & Cancer
October 2022, Vol 13, No 5
Cancer growth and oncology care did not stop during the COVID-19 pandemic, and oncologists, healthcare workers, and patients came together to overcome challenges and produce incredible solutions that may be with us for many years.
Read More
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